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The Pills Are Coming: Lilly’s Orforglipron Oral GLP-1 Weight Loss Pill Shakes Up the Market (PoundsPunch Periodical 2025.08)
Lilly’s once‑daily pill posts late‑stage successes. Here’s what the data really say, how it stacks up against rivals, and what to expect on price, coverage, and patient experience.
2 hours ago3 min read


Novo Nordisk in 2025.07: Navigating Leadership Changes, PBM Dynamics, and Strategic Partnerships in China
Novo Nordisk faced critical leadership changes and mounting challenges from Pharmacy Benefit Managers (PBMs) amid fierce competition in the obesity drug market. With a new CEO recently appointed, the company is also doubling down on strategic partnerships in China, aiming to innovate its research pipeline. However, questions remain about the global acceptance of clinical data from these collaborations and the sustainability of Novo’s market position.
Jul 312 min read


Research Use Only Weight Loss Drugs: Kitchen Chemistry and Loophole Law | PoundsPunch Periodical 2025.06
The “Research Use Only” Peptide Market Isn’t Slowing Down—It’s Evolving
Jun 303 min read


PoundsPunch Periodical 2025.05: Novo Nordisk CEO Shake-Ups and Formularies on Fire in the Obesity-Drug Wars
Novo Nordisk ousted its longtime CEO just two weeks after scoring a major win with CVS Caremark, which named Wegovy its preferred weight-loss drug and dropped Eli Lilly’s Zepbound. But Lilly isn’t flinching. CEO David Ricks dismissed the move as “last decade,” signaling a shift away from exclusive PBM deals and toward direct-to-consumer access. As manufacturers double down on digital pharmacies and price cuts, the real fight for the obesity market may be happening outside the
May 194 min read


PoundsPunch Periodical 2024.04: "Orforglipron??" Why Weight-Loss Drugs Names Sound Like Wi-Fi Passwords
Why do weight-loss drugs have names like Orforglipron? This article breaks down the logic behind drug naming, from science to branding—no jargon, just clarity.
Apr 243 min read


PoundsPunch Periodical 2025.03: The Gray Market for "Research Use Only" Weight Loss Drugs
Experimental weight loss drugs are being sold online for "research use only"—but many are injecting them at home.
Mar 303 min read


Wegovy’s $499 ‘Price Cut’: The Hype, The Reality, and The Part Everyone’s Ignoring
Novo Nordisk just announced Wegovy for $499/month on its direct-to-consumer platform—but is this price cut really a game-changer?
Mar 112 min read


PoundsPunch Periodical 2025.02: FDA Cracks Down on Compounded Semaglutide, Eli Lilly Slashes Zepbound Prices, and Insurance Struggles Continue
FDA Cracks Down on Compounded Semaglutide, Eli Lilly Slashes Zepbound Prices, and Insurance Struggles Continue
Feb 282 min read


PoundsPunch Periodical 2025.01: Medicare Moves to Negotiate Ozempic Prices
Explore Medicare's groundbreaking decision to negotiate Ozempic pricing in PoundsPunch Periodical 2025.01.
Jan 312 min read


PoundsPunch Periodical 2024.12: Weight-Loss Drug Wars Heat Up, PBM Reform Stalls, and Insurers Push Back
Weight-Loss Drug Wars Heat Up, PBM Reform Stalls, and Insurers Push Back
Dec 30, 20246 min read


PoundsPunch Periodical November 2024: Policy Showdowns, Counterfeit Crises, and Industry Disruptions in the Weight-Loss Drug Market
Biden’s Weight-Loss Drug Proposal Faces Trump-Era Challenges, Ireland’s Crackdown on Counterfeits, and China’s Next-Gen GLP-1 Innovations
Nov 30, 20247 min read


Medicare Coverage for Weight Loss Medications Could Cost $35 Billion by 2034, Says CBO
New Proposal to Expand Medicare Coverage Raises Questions on Cost and Potential Savings
Nov 19, 20242 min read


FTC Sues Prescription Drug Middlemen for Inflating Insulin Prices—What Does that Mean?
Caremark, Express Scripts, and OptumRx Face Allegations of Rigging the Rebate System
Nov 19, 20244 min read


PoundsPunch Periodical October 2024
Medicare’s Lower Drug Premiums, Lilly’s Shortage Supply Resolved While Compounding Pharmacies Still in Play
Oct 28, 20243 min read


The US Senate Grills Novo Nordisk on High Prices for Ozempic and Wegovy
A Heated Exchange on the Super Star Weight Loss Drugs' Price, Big Pharma and PBM's Finger-Pointing Game
Sep 26, 20244 min read
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